Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Durham | Syracuse (Regional Transportation Center) | CheapestFastest |
Last refresh of the prices: Yesterday at 2:07 PM EDT.
Compare 2 ways to go from Durham to Syracuse
Among the sustainable travel choices, the Bus stands out as a good way to reach Syracuse. The journey takes about 18 hours, and with fares starting at just $140, it presents an excellent value for a comfortable ride.
Where are the popular stops in Durham and Syracuse?
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Frequently asked questions about travelling from Durham, NC, US to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Durham to Syracuse?
The cheapest bus tickets from Durham to Syracuse start from $140. The average price for this route is around $282. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Syracuse?
The average bus travel time from Durham to Syracuse is 18h, covering a distance of 822 km. The quickest bus can get you there in 17h 40m and is operated by FlixBus.
Which bus companies service the Durham to Syracuse route?
What are the earliest and latest departure times for the bus from Durham to Syracuse?
The earliest bus departs from Durham to Syracuse at 2:40am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from Durham to Syracuse?
A bus trip from Durham to Syracuse generates an estimated 20.5347 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Durham to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12364 reviews.
Which bus company has the best Wi-Fi from Durham to Syracuse?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Durham to Syracuse?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Durham to Syracuse?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Syracuse, US was searched and found on Mar 31, 2026 with a price of $256To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Syracuse, US, as early as possible.
What's the cheapest way to go from Durham, NC, US to Syracuse, US?
The Bus is the cheapest travel choice for this destination
