Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Prague (Central Bus Station Florenc) | Gare routière de Gerland | Cheapest | ||||
| Bus
| Prague (Na Knížecí) | Gare routière de Gerland | Fastest | ||||
| Bus
| Prague (Central Bus Station Florenc) | Gare routière de Gerland | No tags | ||||
| Bus
| Prague (Central Bus Station Florenc) | Gare routière de Gerland | No tags | ||||
| Bus
| Prague (Central Bus Station Florenc) | Gare routière de Gerland | No tags | ||||
| Bus
| Prague (Central Bus Station Florenc) | Lyon | No tags | ||||
| Bus
| Prague (Main Station - parking) | Gare routière de Gerland | No tags | ||||
| Bus
| Prague (Main Station - parking) | Gare routière de Gerland | No tags |
Last refresh of the prices: Last Tuesday at 8:17 PM CEST.
Get from Prague to Lyon
This route is served by bus only
The journey takes about 19 hours 10 minutes, and with fares starting at just $82, it presents an excellent value for a comfortable ride.
20bus per day
19h 10mAverage Duration
858 kmDistance
21kgCO₂ emissions
Bus stations and stops in Prague and Lyon
Stops in Prague
- A
PRG Airport
Aviatická, 161 08, Praha 6, Czechia - B
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic - C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic - E
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia - F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Lyon
- B
Perrache
Rue de Esplanade, 69002 Lyon, France - C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - F
Les Charrières
Les Charrières, 69570 Dardilly, France
Compare companies
3.5 out of 5 stars3.5/516,244 reviews
4.1 out of 5 stars4.1/51,116 reviews
3.7 out of 5 stars3.7/513,013 reviews
FR bus companies:FlixBus, BlaBlaCar Bus, Deutsche Bahn, Sindbad, Ecolines, KLR Bus, RegioJet
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
10-13
$97
10-14
$95
Today
$117
10-16
$115
10-17
No data
10-18
$144
10-19
No data
10-20
No data
The cheapest trip from Prague to Lyon was searched and found on Oct 14, 2026 with a price of $95To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Lyon, as early as possible.
You can expect to pay from $95 to $237 for a bus ticket from Prague to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $115 which is on 2026-10-16.
