Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Florence Station | Greyhound Amtrak Station | CheapestFastest |
Last refresh of the prices: 02/04/2026 EDT.
Compare 2 ways to travel from Florence to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours and with fares starting at just £71, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5784 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi‑Fi. Amtrak ticket prices on this trip start at £242
Frequently asked questions about travelling from Florence, SC, US to Indianapolis by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Florence to Indianapolis?
The cheapest train tickets from Florence to Indianapolis start from £242. The average price for this train route is around £242. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Florence to Indianapolis?
The average train journey time from Florence to Indianapolis is 1d 7h, covering a distance of 521 miles. The fastest train gets you there in 1d 7h and is operated by Amtrak.
Which train operators serve the Florence to Indianapolis route?
Several major train operators run on this route with 1 trains available per day.
What are the earliest and latest departure times for the train from Florence to Indianapolis?
The earliest train from Florence to Indianapolis departs at 22:32. And the latest train departs at 22:32.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Indianapolis was searched and found on 9 Apr 2026 with a price of £233To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Indianapolis as early as possible.
