Bus from Cusco to Arequipa: Tickets & Timetables

Next bus departures

Next departures from Cusco to Arequipa on 18 April
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Turismo MerBus
Terminal Terrestre
Terminal Terrestre ArequipaCheapest
Cruz del SurBus
121 Industrial
ArequipaFastest
ExclucivaBus
Terminal Terrestre
TerrapuertoNo tags
TranszelaBus
Bus terminal of Cusco
ArequipaNo tags
Cruz del SurBus
121 Industrial
ArequipaNo tags

Last refresh of the prices: Today at 12:05 PM -05.

Get from Cusco to Arequipa

This route is served by bus only

The journey takes about 10 hours 50 minutes, and with fares starting at just R 383, it presents an excellent value for a comfortable ride.

3bus per day
10h 50mAverage duration
325 kmDistance
8kgCO₂ emissions

Frequently asked questions about travelling from Cusco to Arequipa by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Cusco to Arequipa?

    The cheapest bus tickets from Cusco to Arequipa start at R 383. The average price for this route is around R 524. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Cusco to Arequipa?

    The average bus journey time from Cusco to Arequipa is 10h 50m, covering a distance of 325 km. The fastest bus gets you there in 10h and is operated by Cruz del Sur.

  3. Which bus companies service the Cusco to Arequipa route?

    Several major bus companies operate on this route with 3 buses available per day, including services from Cruz del Sur, Excluciva, Superciva, Oltursa, Transzela, Turismo Mer.

  4. What is the earliest and latest departure time for the bus from Cusco to Arequipa?

    The earliest bus departs from Cusco to Arequipa at 19:00. And the latest bus departs at 21:30.

  5. What are the CO₂ emissions for the bus trip from Cusco to Arequipa?

    A bus trip from Cusco to Arequipa produces an estimated 8.111475 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Cusco to Arequipa?

    According to Busbud customers, the highest-rated bus company on this route is Cruz del Sur, with an average rating of 4.1 out of 5 stars based on 8116 reviews.

  7. Which bus company has the best Wi-Fi from Cusco to Arequipa?

    Based on reviews on Busbud, the bus company Cruz del Sur has the best Wi-Fi rating with a score of 1.7.

  8. Which bus company offers the most punctual service from Cusco to Arequipa?

    According to Busbud traveller reviews, the most punctual bus company on this route is Cruz del Sur, with a punctuality rating of 4.3 out of 5 stars.

  9. Which bus company has the cleanest buses from Cusco to Arequipa?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Cruz del Sur, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/04
R 457
14/04
R 458
Today
R 457
16/04
R 457
17/04
R 457
18/04
R 457
19/04
R 459
20/04
R 460
busbud logoThe cheapest trip from Cusco to Arequipa was searched and found on 13 Apr 2026 with a price of R 457

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cusco to Arequipa as early as possible.

You can expect to pay from R 457 to R 609 for a bus ticket from Cusco to Arequipa based on the last 2 days. You can expect to find the cheapest price for the trip at R 457, which is on 2026-04-16.

Usually Cruz del Sur will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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