Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Via Gandhi | Terminal Bus Palermo | Cheapest | ||||
| Bus | Via Gandhi | Palermo Via Oreto | Fastest |
Last refresh of the prices: Last Thursday at 2:15 PM CEST.
Get from Comiso to Palermo
The journey takes about 4 hours 50 minutes and with fares starting at just CLP 23,083, it presents an excellent value for a comfortable ride.
Where are the popular stops in Comiso and Palermo?
Stops in Comiso
- A
Fermata dell'autobus Comiso
Viale della Resistenza, 643, 97013 Comiso RG, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Based on 493 reviews, the company was rated 4.3 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the wifi. SAIS Autolinee ticket prices on this trip start at CLP 23,083
Frequently asked questions about traveling from Comiso to Palermo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Comiso to Palermo?
The cheapest bus tickets from Comiso to Palermo start from CLP 23,083. The average price for this route is around CLP 23,587. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Comiso to Palermo?
The average bus trip duration from Comiso to Palermo is 4h 50m, covering a distance of 104 miles (168 km). The quickest bus can get you there in 4h 50m and is operated by SAIS Autolinee.
Which bus companies service the Comiso to Palermo route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Comiso to Palermo?
The earliest bus departs from Comiso to Palermo at 6:40am. And the latest bus departs at 6:40am.
What are the CO₂ emissions for the bus trip from Comiso to Palermo?
A bus trip from Comiso to Palermo generates an estimated 4.187825 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Comiso to Palermo was searched and found on Apr 28, 2026 with a price of CLP 21,220To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Comiso to Palermo, as early as possible.
You can expect to pay from CLP 21,220 to CLP 21,413 for a bus ticket from Comiso to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 21,220 which is on 2026-04-28.
