Bus and Train from Santander to Madrid: Tickets & Schedules
Next available departures
Next departures for Santander to Madrid on June 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander
Madrid-Chamartin
CheapestFastest
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Santander
Madrid-Chamartin
No tags
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander
Madrid-Chamartin
No tags
Next departures for Santander to Madrid on June 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander (Estacion de Autobuses)
Avenida de América Metro
Cheapest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Fastest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Next departures for Santander to Madrid on June 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander
Madrid-Chamartin
Cheapest
Santander
Madrid-Chamartin
Fastest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander
Madrid-Chamartin
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Next departures for Santander to Madrid on June 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander
Madrid-Chamartin
Cheapest
Santander
Madrid-Chamartin
Fastest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander
Madrid-Chamartin
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Next departures for Santander to Madrid on June 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander (Estacion de Autobuses)
Avenida de América Metro
Cheapest
Santander
Madrid-Chamartin
Fastest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander
Madrid-Chamartin
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Next departures for Santander to Madrid on June 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander (Estacion de Autobuses)
Avenida de América Metro
Cheapest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Fastest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Next departures for Santander to Madrid on June 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Santander (Estacion de Autobuses)
Moncloa
Cheapest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Fastest
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Santander (Estacion de Autobuses)
Avenida de América Metro
No tags
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
No tags
Last refresh of the prices: Today at 6:52 PM CEST.
Compare 2 ways to go from Santander to Madrid
We recommend taking the train
Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 24 minutes and with fares starting at just CLP 23,584, it presents an excellent value for a comfortable ride.
According to 41 reviews, ALSA received a 4.4-star rating for this journey. Travelers were especially satisfied with the staff and the timeliness, but some complained about the temperature. ALSA ticket prices on this trip start at CLP 45,505
ALSA Santander Madrid recent customer reviews
To indicate in english that the bus is stopping in Burgos for a while would be great. The information was given only in spanish.
5.0 out of 5 stars
Anita K.
I did not have any contact with staff other than when the driver took my ticket so really I cannot really rate them, otherwise the trip was very smooth.
5.0 out of 5 stars
Terence P.
Free cold water was a bonus and much needed thankyou
Bus very clean and nice having movies
Based on 1019 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the staff and the temperature but often complained with the wifi. Renfe ticket prices on this trip start at CLP 23,584
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Santander to Madrid by bus or train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is a ticket from Santander to Madrid?
The cheapest tickets from Santander to Madrid start from CLP 23,584. The average price for this route is around CLP 47,116. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the ride from Santander to Madrid?
The average trip duration from Santander to Madrid is 4h 57m, covering a distance of 207 miles (334 km). The quickest vehicle can get you there in 4h 16m and is operated by Renfe.
Which companies service the Santander to Madrid route?
Several major companies operate on this route with 6 trips available per day, including services from ALSA, FlixBus, Renfe.
What is the earliest and latest departure time from Santander to Madrid?
The earliest trip departs from Santander to Madrid at 12:45am. And the latest trip departs at 7:20pm.
What are the CO₂ emissions for the trip from Santander to Madrid?
A trip from Santander to Madrid generates an estimated 8.325475 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best company from Santander to Madrid?
According to Busbud customers, the highest-rated company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 62253 reviews.
Which company has the best Wi-Fi from Santander to Madrid?
Based on reviews on Busbud, the company ALSA has the best Wi-Fi rating with a score of 3.5.
Which company has the most timely service from Santander to Madrid?
According to Busbud traveler reviews, the most timely company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which company has the cleanest vehicles from Santander to Madrid?
According to Busbud traveler reviews, the company with the cleanest vehicles on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses and trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
06/20
CLP 39,031
06/21
CLP 43,080
Today
CLP 38,631
06/23
CLP 38,975
06/24
CLP 37,554
06/25
CLP 38,640
06/26
CLP 38,966
06/27
CLP 39,514
The cheapest trip from Santander to Madrid was searched and found on Jun 24, 2026 with a price of CLP 37,554
To save money and be sure you have the best seat, it's a good idea to buy your bus and train tickets from Santander to Madrid, as early as possible.
You can expect to pay from CLP 37,554 to CLP 73,565 for a bus or train ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 37,554 which is on 2026-06-24.
Usually ALSA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Santander to Madrid was searched and found on Jun 24, 2026 with a price of CLP 37,554
