Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Chicago 95Th & Dan Ryan | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Downtown Greyhound Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Downtown Greyhound Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Downtown Greyhound Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | 537-517 W. Jackson Blvd | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 11:49 PM EDT.
Compare 2 ways to go from Jacksonville to Chicago
Among the sustainable travel choices, the Bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 55 minutes, and with fares starting at just ARS 139,946, it presents an excellent value for a comfortable ride.
Bus stations and stops in Jacksonville and Chicago
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Frequently asked questions about travelling from Jacksonville, FL to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Jacksonville to Chicago?
The cheapest bus tickets from Jacksonville to Chicago start from ARS 139,946. The average price for this route is around ARS 215,220. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to Chicago?
The average bus travel time from Jacksonville to Chicago is 1d 2h, covering a distance of 1391 km. The quickest bus can get you there in 1d and is operated by FlixBus.
Which bus companies service the Jacksonville to Chicago route?
What are the earliest and latest departure times for the bus from Jacksonville to Chicago?
The earliest bus departs from Jacksonville to Chicago at 9:05am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Jacksonville to Chicago?
A bus trip from Jacksonville to Chicago generates an estimated 34.75275 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Jacksonville to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88149 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Chicago?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Jacksonville to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Chicago was searched and found on Sep 22, 2026 with a price of ARS 161,415To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Chicago, as early as possible.
You can expect to pay from ARS 161,415 to ARS 428,421 for a bus ticket from Jacksonville, FL to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 161,415 which is on 2026-09-22.
What's the cheapest way to go from Jacksonville, FL to Chicago?
The Bus is the cheapest travel choice for this destination
