Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Gateway Station | ||||
 | Bus | Tupelo (Brothers Quick Stop) | Gateway Station | ||||
| Bus | Tupelo (Brothers Quick Stop) | Gateway Station | ||||
FlixBus + Greyhound | Bus | Tupelo (Brothers Quick Stop) | Gateway Station | ||||
| Bus | Tupelo (Brothers Quick Stop) | Gateway Station |
Get from Tupelo to St. Louis
The journey takes about 18 hours 10 minutes, and with fares starting at just CLP 86,101, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 88074 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at CLP 86,101
Frequently asked questions about travelling from Tupelo to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to St. Louis?
The cheapest bus tickets from Tupelo to St. Louis start from CLP 86,101. The average price for this route is around CLP 115,396. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to St. Louis?
The average bus travel time from Tupelo to St. Louis is 18h 10m, covering a distance of 507 km. The quickest bus can get you there in 18h 10m and is operated by Greyhound.
Which bus companies service the Tupelo to St. Louis route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Tupelo to St. Louis?
The earliest bus departs from Tupelo to St. Louis at 5:35am. And the latest bus departs at 9:45pm.
What are the CO₂ emissions for the bus trip from Tupelo to St. Louis?
A bus trip from Tupelo to St. Louis generates an estimated 12.662300000000002 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to St. Louis was searched and found on Aug 19, 2026 with a price of CLP 79,327To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to St. Louis, as early as possible.
