Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus
| Baltimore Bus Stop | Florence, SC | Cheapest | ||||
 | Bus
| O'Donnell St. & Travel Plaza, Infront of TA Gas station | 2301 W Lucas St. | Fastest | ||||
 | Bus
| Baltimore Downtown Bus Station | Florence, SC | No tags | ||||
 | Bus
| Baltimore Downtown Bus Station | Bus station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Baltimore Downtown Bus Station | Bus station | No tags | ||||
| Bus
| Baltimore Downtown Bus Station | Bus station | No tags | ||||
| Bus
| Baltimore Bus Stop | Bus station | No tags |
Last refresh of the prices: Yesterday at 11:23 AM EDT.
Compare 2 ways to travel from Baltimore to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 11 hours 5 minutes and with fares starting at just R 970, it presents an excellent value for a comfortable ride.
Bus stations and stops in Baltimore and Florence
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B
Penn Station
7 St Paul St, Baltimore, MD 21201, USA - C
Maryland Ave & I-83
1578 Maryland Ave, Baltimore, MD 21201, USA
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Baltimore to Florence, SC, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Baltimore to Florence?
The cheapest bus tickets from Baltimore to Florence start at R 970. The average price for this route is around R 1 378. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Baltimore to Florence?
The average bus journey time from Baltimore to Florence is 11h 5m, covering a distance of 631 km. The fastest bus gets you there in 8h 15m and is operated by FlixBus.
Which bus companies service the Baltimore to Florence route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, FlixBus, Wanda Coach.
What is the earliest and latest departure time for the bus from Baltimore to Florence?
The earliest bus departs from Baltimore to Florence at 02:20. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Baltimore to Florence?
A bus trip from Baltimore to Florence produces an estimated 15.7604 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Baltimore to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88213 reviews.
Which bus company has the best Wi-Fi from Baltimore to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Baltimore to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Baltimore to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Baltimore to Florence, SC, US was searched and found on 19 Oct 2026 with a price of R 942To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, SC, US as early as possible.
You can expect to pay from R 942 to R 2 597 for a bus ticket from Baltimore to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 942, which is on 2026-10-19.
Usually FlixBus, Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Baltimore to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
