Previously seen trips

Next departures for Baltimore to Florence on September 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
FlixBus + Greyhound	Bus Wifi Toilet Power outlets	1:55am	Baltimore Downtown Bus Station	10h 50m	12:45pm	Bus station
Greyhound + FlixBus	Bus Wifi Toilet Power outlets	1:55am	Baltimore Downtown Bus Station	10h 50m	12:45pm	Bus station
Greyhound + FlixBus	Bus Wifi Toilet Power outlets	2:50pm	Baltimore Bus Stop	14h 55m	5:45am	Florence, SC
FlixBus + Greyhound	Bus Wifi Toilet Power outlets	2:50pm	Baltimore Bus Stop	14h 55m	5:45am	Florence, SC
	Bus Wifi Toilet Power outlets	8:30pm	Baltimore Downtown Bus Station	9h 15m	5:45am	Florence, SC

Compare 2 ways to go from Baltimore to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 11 hours 5 minutes and with fares starting at just R$304, it presents an excellent value for a comfortable ride.

6bus per day

11h 5mAverage Duration

391 milesDistance

16kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceR$304 - R$1,186	Average Duration11h 5m	CO₂ emissions 16kg CO₂e
Train	Average PriceR$430 - R$1,436	Average Duration9h 37m	CO₂ emissions 57kg CO₂e

Bus stations and stops in Baltimore and Florence

Stops in Baltimore

A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States
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B
Penn Station
7 St Paul St, Baltimore, MD 21201, USA
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C
Maryland Ave & I-83
1578 Maryland Ave, Baltimore, MD 21201, USA
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D
Baltimore Airport
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Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
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B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/588,177 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/515,908 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Wanda Coach

2.6/5779 reviews

Staff2.9

Timeliness2.8

Cleanliness2.5

Wifi1.6

Wanda Coach is one of the main Chinatown bus carriers in the US, connecting about 75 cities around the country with inexpensive tickets and comfortable bus rides. Wanda Coach buses travel between Chinatown neighborhoods with direct buses that are affordable, safe and have convenient pick-up and drop-off locations. If you travel with Wanda Coach, you can reschedule your tickets for a $10 fee up to 2 hours before travel time, and their buses have free WiFi, power outlets and bathrooms.

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Baltimore to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Baltimore to Florence?
The cheapest bus tickets from Baltimore to Florence start from R$304. The average price for this route is around R$437. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Baltimore to Florence?
The average bus trip duration from Baltimore to Florence is 11h 5m, covering a distance of 391 miles (631 km). The quickest bus can get you there in 8h 15m and is operated by FlixBus.
Which bus companies service the Baltimore to Florence route?
Several major bus companies operate on this route with 6 buses available per day, including services from Greyhound, FlixBus, Wanda Coach.
What is the earliest and latest departure time for the bus from Baltimore to Florence?
The earliest bus departs from Baltimore to Florence at 2:20am. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Baltimore to Florence?
A bus trip from Baltimore to Florence generates an estimated 15.76 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Baltimore to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88168 reviews.
Which bus company has the best Wi-Fi from Baltimore to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Baltimore to Florence?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Baltimore to Florence?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/25

R$532

09/26

R$383

Today

R$290

09/28

R$266

09/29

R$242

09/30

R$266

10/01

R$351

10/02

R$308

The cheapest trip from Baltimore to Florence, SC, US was searched and found on Sep 29, 2026 with a price of R$242

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Florence, SC, US, as early as possible.

You can expect to pay from R$242 to R$563 for a bus ticket from Baltimore to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at R$242 which is on 2026-09-29.

Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.