Next bus departures

Next departures for Florence to Orlando on August 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	12:10pm	Bus station	17h 40m	5:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	12:10pm	Bus station	19h 40m	7:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	15h 40m	7:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:20pm	Bus station	1d 1h	9:15pm	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	22h 45m	2:55pm	The Florida Mall	No tags

Next departures for Florence to Orlando on August 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:45am	Florence, SC	8h 25m	2:10pm	Orlando Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	12:10pm	Bus station	17h 40m	5:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	12:10pm	Bus station	19h 40m	7:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	15h 40m	7:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:20pm	Bus station	1d 1h	9:15pm	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	22h 45m	2:55pm	The Florida Mall	No tags

Next departures for Florence to Orlando on August 11
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	7:20pm	Bus station	1d 1h	9:15pm	Orlando Bus Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	4:10pm	Bus station	15h 40m	7:50am	Orlando Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	12:05am	Florence, SC	21h 10m	9:15pm	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	12:10pm	Bus station	17h 40m	5:50am	Orlando Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	12:10pm	Bus station	19h 40m	7:50am	Orlando Bus Station	No tags

Last refresh of the prices: Today at 10:53 AM EDT.

Compare 2 ways to go from Florence to Orlando

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Orlando. The journey takes about 9 hours 46 minutes and with fares starting at just R 1 289, it presents an excellent value for a comfortable ride.

1train per day

9h 46mAverage Duration

403 milesDistance

59kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceR 993 - R 4 449	Average Duration17h 40m	CO₂ emissions 16kg CO₂e
Train	Average PriceR 1 289 - R 18 567	Average Duration9h 46m	CO₂ emissions 59kg CO₂e

Bus stations and stops in Florence and Orlando

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Orlando

A
Orlando Bus Station
555 N John Young Pkwy, Orlando, FL 32805
Visit page
B
Orlando RedCoach Station
RedCoach Station, 1777 McCoy Road, Orlando, FL 32809
Visit page
C
Jet Set Express Terminal
Jet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
Visit page
D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830
E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA
F
Seaworld Hotels
10100 International Drive , Orlando, 32821

Compare bus companies

FlixBus

3.5/514,999 reviews

Staff4.1

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/588,028 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about traveling from Florence, SC, US to Orlando by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Orlando?
The cheapest bus tickets from Florence to Orlando start from R 993. The average price for this route is around R 1 874. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Orlando?
The average bus trip duration from Florence to Orlando is 17h 40m, covering a distance of 402 miles (649 km). The quickest bus can get you there in 8h 25m and is operated by FlixBus.
Which bus companies service the Florence to Orlando route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Florence to Orlando?
The earliest bus departs from Florence to Orlando at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Orlando?
A bus trip from Florence to Orlando generates an estimated 16.2017 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Orlando?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 14951 reviews.
Which bus company has the best Wi-Fi from Florence to Orlando?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Orlando?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Florence to Orlando?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/04

R 923

08/05

R 1 074

Today

R 1 863

08/07

R 1 410

08/08

R 1 292

08/09

R 1 326

08/10

No data

08/11

No data

The cheapest trip from Florence, SC, US to Orlando was searched and found on Aug 4, 2026 with a price of R 923

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Orlando, as early as possible.

You can expect to pay from R 923 to R 1 863 for a bus ticket from Florence, SC, US to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 292 which is on 2026-08-08.