Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Niagara Frontier Transportation Authority | Florence, SC | No tags | ||||
| Bus | Buffalo (BUF) Airport | Florence, SC | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Florence, SC | No tags | ||||
| Bus | Buffalo (BUF) Airport | Florence, SC | No tags | ||||
| Bus | Niagara Frontier Transportation Authority | Florence, SC | No tags |
Compare 2 ways to go from Buffalo to Florence
Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 1 day, 5 hours 46 minutes, and with fares starting at just $151, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Florence?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Frequently asked questions about travelling from Buffalo, NY to Florence, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Florence?
The cheapest bus tickets from Buffalo to Florence start from $151. The average price for this route is around $275. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Florence?
The average bus travel time from Buffalo to Florence is 1d 5h, covering a distance of 970 km. The quickest bus can get you there in 1d and is operated by FlixBus.
Which bus companies service the Buffalo to Florence route?
What are the earliest and latest departure times for the bus from Buffalo to Florence?
The earliest bus departs from Buffalo to Florence at 12:55am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Florence?
A bus trip from Buffalo to Florence generates an estimated 24.249950000000002 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Buffalo to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12448 reviews.
Which bus company has the best Wi-Fi from Buffalo to Florence?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Buffalo to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Florence, SC, US was searched and found on Apr 12, 2026 with a price of $437To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Florence, SC, US, as early as possible.
What's the cheapest way to go from Buffalo, NY to Florence, SC, US?
The Bus is the cheapest travel choice for this destination
