Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Key West Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Key West Bus Station | Downtown Transit Center | No tags | ||||
Greyhound + FlixBus | Bus | Key West Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Key West Bus Station | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Key West Bus Station | Downtown Transit Center | No tags |
Get from Key West to Indianapolis
The journey takes about 1 day, 11 hours 25 minutes and with fares starting at just $175, it presents an excellent value for a comfortable ride.
Where are the popular stops in Key West and Indianapolis?
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Key West to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Key West to Indianapolis?
The cheapest bus tickets from Key West to Indianapolis start from $175. The average price for this route is around $220. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Key West to Indianapolis?
The average bus trip duration from Key West to Indianapolis is 1d 11h, covering a distance of 1080 miles (1741 km). The quickest bus can get you there in 1d 11h and is operated by Greyhound.
Which bus companies service the Key West to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Key West to Indianapolis?
The earliest bus departs from Key West to Indianapolis at 10:00am. And the latest bus departs at 5:00pm.
What are the CO₂ emissions for the bus trip from Key West to Indianapolis?
A bus trip from Key West to Indianapolis generates an estimated 43.520825 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Key West to Indianapolis was searched and found on May 2, 2026 with a price of $182To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key West to Indianapolis, as early as possible.
